RP03514
Recombinant Mouse CD63 Protein
Size
£318.00
- SKU:
- RP03514
- Additional Names:
- Cd63,CD63 antigen, CD63
- Molecular Weight:
- 10-25 kDa
- Purity:
- ≥90%
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Ala103-Ile203
- Formulation:
- Recombinant Mouse CD63 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala103-Ile203) of Mouse CD63 (Accession #NP_031679.1) fused with No tag .
- Species:
- Human, Mouse
- Uniprot:
- P41731
- Synonyms:
- C75951;CD63 antigen;ME491;melanoma 1 antigen;Tsp;Tspan30
- Extra Details:
- Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
- Shipping Conditions:
- Blue Ice