RP03285
Recombinant Human Neutrophil cytosol factor 1/NCF1 Protein
Size
£193.00
- SKU:
- RP03285
- Additional Names:
- 47 kDa autosomal chronic granulomatous disease protein|47 kDa neutrophil oxidase factor|NCF-1|NCF-47K|NCF1|Neutrophil cytosol factor 1|Neutrophil NADPH oxidase factor 1|Nox organizer 2|NOXO2|p47-phox|SH3PXD1A
- Molecular Weight:
- 45-50 kDa
- Purity:
- ≥95%
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Met1-Val390
- Formulation:
- Recombinant Human Neutrophil cytosol factor 1/NCF1 Protein is produced by E.coli expression system. The target protein is expressed with sequence (Met1-Val390) of human Neutrophil cytosol factor 1/NCF1 (Accession #P14598) fused with His tag at the C-terminus.
- Species:
- Human
- Sequence:
- MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCSTLMSLPTKISRCPHLLDFFKVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSKPQPAVPPRPSADLILNRCSESTKRKLASAV
- Uniprot:
- P14598
- Synonyms:
- 47 kDa autosomal chronic granulomatous disease protein;47 kDa neutrophil oxidase factor;CGD1;NADPH oxidase organizer 2;NCF-1;NCF-47K;NCF1A;neutrophil cytosol factor 1;neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1);neutrophil NADPH oxidase factor 1;nox organizer 2;nox-organizing protein 2;NOXO2;p47-phox;p47phox;SH3 and PX domain-containing protein 1A;SH3PXD1A
- Extra Details:
- NCF1 is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This protein is essential for activation of the NADPH oxidase complex, which is essential for superoxide production. It cooperates with NCF2 to form a core association in the complex, interacting with NCF4, CYBB and CYBA. Mutations in the NCF1 gene have been associated with chronic granulomatous disease.
- Shipping Conditions:
- Blue Ice