Recombinant Human TSHR Protein

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£574.00

SKU:: RP03264
Additional Names:: CHNG1|LGR3|Thyroid-stimulating hormone receptor|Thyrotropin receptor|TSH-R|TSHR|TSHR-I
Molecular Weight:: 50-60 kDa
Purity:: ≥85%
Storage Conditions:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Immunogen:: Gly21-Gly413
Formulation:: Recombinant Human TSHR Protein is produced by Baculovirus-Insect Cells expression system. The target protein is expressed with sequence (Gly21-Gly413) of human TSHR (Accession #NP_000360.2) fused with His tag at the C-terminus.
Species:: Human
Sequence:: GMGCSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETLTLKLYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLLDVSQTSVTALPSKGLEHLKELIARNTWTLKKLPLSLSFLHLTRADLSYPSHCCAFKNQKKIRGILESLMCNESSMQSLRQRKSVNALNSPLHQEYEENLGDSIVGYKEKSKFQDTHNNAHYYVFFEEQEDEIIGFGQELKNPQEETLQAFDSHYDYTICGDSEDMVCTPKSDEFNPCEDIMG
Uniprot:: P16473
Synonyms:: CHNG1;hTSHR-I;LGR3;seven transmembrane helix receptor;Thyroid-stimulating hormone receptor;thyrotropin receptor;thyrotropin receptor-I, hTSHR-I;TSH receptor
Extra Details:: Thyroid-stimulating hormone receptor (TSHR) is the receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. TSH is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. The activity of TSHR is mediated by G proteins which activate adenylate cyclase.

Shipping Conditions:: Blue Ice