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RP03258

Recombinant Human NUDT5 Protein

Size

£395.00

SKU:
RP03258
Additional Names:
ADP-sugar pyrophosphatase|HSPC115|Nudix motif 5|NUDIX5|NUDT5|YSA1|YSA1H
Molecular Weight:
30-35 kDa
Purity:
≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Immunogen:
Met1-Phe219
Formulation:
Recombinant Human NUDT5 Protein is produced by E.coli expression system. The target protein is expressed with sequence (Met1-Phe219) of human NUDT5 (Accession #Q9UKK9) fused with His tag at the N-terminus.
Species:
Human
Sequence:
MESQEPTESSQNGKQYIISEELISEGKWVKLEKTTYMDPTGKTRTWESVKRTTRKEQTADGVAVIPVLQRTLHYECIVLVKQFRPPMGGYCIEFPAGLIDDGETPEAAALRELEEETGYKGDIAECSPAVCMDPGLSNCTIHIVTVTINGDDAENARPKPKPGDGEFVEVISLPKNDLLQRLDALVAEEHLTVDARVYSYALALKHANAKPFEVPFLKF
Uniprot:
Q9UKK9
Synonyms:
8-oxo-dGDP phosphatase;ADP-sugar pyrophosphatase;hNUDT5;nuclear ATP-synthesis protein NUDIX5;Nucleoside diphosphate-linked moiety X motif 5;nudix (nucleoside diphosphate linked moiety X)-type motif 5;YSA1;YSA1H;YSAH1
Extra Details:
NUDIX hydrolase type 5 (NUDT5) is a kind of ADP-ribose pyrophosphatase and nucleotide metabolizing enzyme that can either act as an ADP-sugar pyrophosphatase in absence of diphosphate or catalyze the synthesis of ATP in presence of diphosphate. In absence of diphosphate, NUDT5 hydrolyzes with similar activities various modified nucleoside diphosphates such as ADP-ribose, ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. In presence of diphosphate, NUDT5 mediates the synthesis of ATP in the nucleus by catalyzing the conversion of ADP-ribose to ATP and ribose 5-phosphate.
Shipping Conditions:
Blue Ice