Recombinant Human XPNPEP3 Protein

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£459.00

Was £540.00

SKU:: RP03207LQ
Additional Names:: Aminopeptidase P3|APP3|Probable Xaa-Pro Aminopeptidase 3|X-Pro Aminopeptidase 3|XPNPEP3
Molecular Weight:: 65 KDa
Purity:: ≥95%
Storage Conditions:: -70[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Immunogen:: Met1-Ser507
Formulation:: Recombinant Human XPNPEP3 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Ser507) of Human XPNPEP3 (Accession #NP_071381.1) fused with a 6His tag at the N-terminus, 6His tag at the C-terminus.
Species:: Human
Uniprot:: Q9NQH7
Synonyms:: Aminopeptidase P3;APP3;ICP55;Intermediate Cleaving Peptidase 55;NPHPL1;probable Xaa-Pro aminopeptidase 3;X-Pro aminopeptidase 3;X-prolyl aminopeptidase 3, mitochondrial;xaa-Pro aminopeptidase 3
Extra Details:: Probable Xaa-Pro Aminopeptidase 3 (XPNPEP3) is a member of the peptidase M24B family. XPNPEP3 has two isoforms and both are widely expressed. XPNPEP3 is localized in the Mitochondrion. XPNPEP3 catalyzes the release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Defects in XPNPEP3 are the cause of nephronophthisis-like nephropathy type 1 which is a disorder with features of nephronophthisis, a cystic kidney disease leading to end-stage renal failure.