RP03157
Recombinant Human LYVE-1 Protein
Size
£163.00
- SKU:
- RP03157
- Additional Names:
- Cell Surface Retention Sequence-Binding Protein 1|CRSBP-1|CRSBP1|Extracellular Link Domain-Containing Protein 1|HAR|Hyaluronic Acid Receptor|Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1|LYVE-1|LYVE1|XLKD1
- Molecular Weight:
- 45-50 kDa
- Purity:
- ≥95%
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Leu20-Thr238
- Formulation:
- Recombinant Human LYVE-1 Protein is produced by HEK293 Cells expression system. The target protein is expressed with sequence (Leu20-Thr238) of human LYVE-1 (Accession #AAH26231.1) fused with His tag at the C-terminus.
- Species:
- Human
- Uniprot:
- Q9Y5Y7
- Synonyms:
- cell surface retention sequence binding protein-1;Cell surface retention sequence-binding protein 1;CRSBP-1;extracellular link domain-containing 1;extracellular link domain-containing protein 1;HAR;hyaluronic acid receptor;lymphatic vessel endothelial hyaluronic acid receptor 1;LYVE-1;XLKD1
- Extra Details:
- Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is a single-pass type I membrane protein. LYVE-1 is a CD44 homolog found primarily on lymphatic endothelial cells 1. LYVE-1 mainly expressed in endothelial cells lining lymphatic vessels. While LYVE-1 functions is a Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. LYVE-1 plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). It may act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
- Shipping Conditions:
- Blue Ice