RP03141
Recombinant Human GFAP protein
Size
£193.00
- SKU:
- RP03141
- Additional Names:
- Glial fibrillary acidic protein, GFAP
- Molecular Weight:
- 18 KDa
- Purity:
- ≥95%
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Leu292-Met432
- Formulation:
- Recombinant Human GFAP Protein is produced by E. coli expression system. The target protein is expressed with sequence (Leu292-Met432) of Human GFAP (Accession #NP_002046.1) fused with His tag at the N-terminus.
- Species:
- Human
- Sequence:
- LTCDLESLRGTNESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM
- Uniprot:
- P14136
- Synonyms:
- ALXDRD;glial fibrillary acidic protein
- Extra Details:
- Glial Fibrillary Acidic Protein (GFAP) is an intermediate filament (IF) protein which belongs to the intermediate filament family. GFAP is expressed in numerous cell types of the central nervous system (CNS), ependymal cells and phosphorylated by PKN1. GFAP, a class-III intermediate filament, is a cell-specific marker during the development of the central nervous system and distinguishes astrocytes from other glial cells. It is closely related to its non-epithelial family members, vimentin, desmin, and peripherin, which are all involved in the structure and function of the cell's cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cells but its exact function remains poorly understood.
- Shipping Conditions:
- Blue Ice