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RP02970

Recombinant Human SFRP2 Protein

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£621.00

SKU:
RP02970
Additional Names:
SFRP2, FRP2, SARP1, FKSG12, UNQ361/PRO697,Secreted frizzled-related protein 2, FRP-2, sFRP-2, Secreted apoptosis-related protein 1, SARP-1
Molecular Weight:
34-38 kDa
Purity:
≥95%
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Immunogen:
Leu25-Cys295
Formulation:
Recombinant Human SFRP2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu25-Cys295) of human SFRP2 (Accession #NP_003004.1) fused with a 6xHis tag at the C-terminus.
Species:
Human
Uniprot:
Q96HF1
Synonyms:
FRP-2;SARP-1;SARP1;SDF-5;secreted apoptosis related protein 1;Secreted apoptosis-related protein 1;secreted frizzled-related protein 2;sFRP-2;testicular tissue protein Li 170
Extra Details:
As biomarkers, DNA methylation is used to detect colorectal cancer (CRC) and make assessment of CRC prognosis. The published findings showed the association between the methylation of SFRP1, SFRP2, and WIF1, located in the Wnt signaling pathway, and the prognosis of CRC were not consistent. SFRP1, SFRP2, and WIF1 were frequently hypermethylated in CRC tumor tissues. It was apparent that the promoter hypermethylation of SFRP2 and co-hypermethylation of SFRP1 and SFRP2 might be considered as independent prognostic predictors for survival advantage of postoperative CRC patients.
Shipping Conditions:
Blue Ice