RP02953
Recombinant Human LRG1 Protein
Size
£145.00
- SKU:
- RP02953
- Additional Names:
- LRG1, LRG, Leucine-rich alpha-2-glycoprotein, LRG
- Molecular Weight:
- 45-60 kDa
- Purity:
- ≥95%
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Vla36-Gln347
- Formulation:
- Recombinant Human LRG1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Vla36-Gln347) of Human LRG1 fused with His tag at the C-terminus.
- Species:
- Human
- Uniprot:
- P02750
- Synonyms:
- 1300008B03Rik;2310031E04Rik;HMFT1766;leucine rich alpha 2 glycoprotein;leucine-rich alpha-2-glycoprotein;LRG
- Extra Details:
- LRG1 is a Protein Coding gene. LRG1 belongs to the leucine-rich repeat (LRR) family. Members of this family are involved in protein-protein interaction, signal transduction, and cell adhesion and development. LRG1 is expressed during granulocyte differentiation. It contains 4 LIM zinc-binding domains and 1 Rho-GAP domain. LRG1 is involved in promoting neovascularization (new blood vessel growth) by causing a switch in transforming growth factor-beta (TGFbeta) signaling in endothelial cells. LRG1 binds to the accessory receptor endoglin and promotes signaling via the ALK1-Smad1/5/8 pathway. It may be a potential therapeutic target for the treatment of diseases where there is aberrant neovascularization. Diseases associated with LRG1 include Appendicitis and Normal Pressure Hydrocephalus.
- Shipping Conditions:
- Blue Ice