RP02727
Recombinant Cynomolgus IL-31 Protein
Size
£508.00
- SKU:
- RP02727
- Additional Names:
- Interleukin-31; IL-31; IL31
- Molecular Weight:
- 23-30 kDa
- Purity:
- ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Leu27-Thr163
- Formulation:
- Recombinant Cynomolgus IL-31 Protein is expressed from Expi293 with His tag at the N-terminal.; It contains Leu27-Thr163.
- Species:
- Non-human Primate
- Uniprot:
- G7PJ78-1
- Synonyms:
- interleukin-31
- Extra Details:
- Many autoimmune skin diseases, such as bullous pemphigoid (BP), psoriasis and certain types of chronic urticaria, are associated with intensive pruritus. While histamine and neuropeptides have previously been ascribed to play a role in itch that accompanies these diseases, recent evidence suggests that the pruritogenic cytokine interleukin (IL)-31 is a major driver of pruritic responses. IL-31 was originally shown to be produced by activated helper T cells, particularly Th2 cells, mast cells, macrophages and dendritic cells.
- Shipping Conditions:
- Blue Ice