RP02707
Recombinant Human Notch 3 Protein
Size
£431.00
- SKU:
- RP02707
- Additional Names:
- CADASIL|Notch homolog 3|Notch-3|NOTCH3
- Molecular Weight:
- 53-60 kDa
- Purity:
- ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Ala40-Glu467
- Formulation:
- Recombinant Human Notch 3 Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal.; It contains Ala40-Glu467.
- Species:
- Human
- Uniprot:
- Q9UM47
- Synonyms:
- CADASIL;CADASIL1;CASIL;IMF2;LMNS;neurogenic locus notch homolog protein 3;notch 3;Notch homolog 3
- Extra Details:
- Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes. The extracellular domain of Notch receptors interact with the extracellular domain of transmembrane ligands Jagged, Delta, and Serrate expressed on the surface of a neighboring cell. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs
- Shipping Conditions:
- Blue Ice