RP02657
Recombinant Human EPHB2 Protein
Size
£336.00
- SKU:
- RP02657
- Additional Names:
- CAPB|Cek5|DRT|EK5|EphB2|EPHT3|EPHT3MGC87492|ERK|HEK5|Nuk|PCBC|Qek2|Sek3|TYRO5
- Molecular Weight:
- 65-75 kDa
- Purity:
- ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Val19-Leu543
- Formulation:
- Recombinant Human EPHB2 Protein is expressed from Expi293 with His tag at the C-terminal.; It contains Val19-Leu543.
- Species:
- Human
- Uniprot:
- P29323-1
- Synonyms:
- BDPLT22;CAPB;developmentally-regulated Eph-related tyrosine kinase;DRT;EK5;elk-related tyrosine kinase;eph tyrosine kinase 3;EPH-like kinase 5;ephrin type-B receptor 2;EPHT3;ERK;Hek5;PCBC;protein-tyrosine kinase HEK5;renal carcinoma antigen NY-REN-47;Tyro5;tyrosine-protein kinase receptor EPH-3;tyrosine-protein kinase TYRO5
- Extra Details:
- EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endothelial-mesenchymal transition (EMT) and elicits associated pathologic characteristics of glioblastoma multiforme (GBM) such as invasion and migration. EPHB2 is epigenetically overexpressed in hypoxia, a condition highly prevalent in malignancy. Furthermore, HIF-2A Alpha is required for EPHB2 stabilization by hypoxia.
- Shipping Conditions:
- Blue Ice