RP02638
Recombinant Cynomolgus SIRP-alpha/CD172a Protein
Size
£353.00
- SKU:
- RP02638
- Additional Names:
- BIT|CD172a|MFR|MYD-1|MYD1|P84|PTPNS1|SHP substrate 1|SHPS-1|SHPS1|SHPS1CD172A|SIRP alpha|Sirp-alpha-1|Sirp-alpha-2|Sirp-alpha-3|SIRPA|SIRPalpha2
- Molecular Weight:
- 60-70 kDa
- Purity:
- ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Glu31-Arg370
- Formulation:
- Recombinant Cynomolgus SIRP-alpha/CD172a Protein is produced by Expi293 expression system. The target protein is expressed with sequence ( Glu31-Arg370) of Cynomolgus CD172a fused with His tag at the C-terminus.
- Species:
- Non-human Primate
- Uniprot:
- I7G9Z7
- Synonyms:
- signal-regulatory protein beta-1;tyrosine-protein phosphatase non-receptor type substrate 1
- Extra Details:
- Signal regulatory protein A Alpha (SIRPA Alpha) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPA Alpha acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don't eat me" signal.Cancer cells highly expressed CD47 that activate SIRP A Alpha and inhibit macrophage-mediated destruction.
- Shipping Conditions:
- Blue Ice