Recombinant Human MMP-8 Protein

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£163.00

SKU:: RP02626
Additional Names:: CLG1|Collagenase 2|HNC|MMP-8|MMP8|PMNL-CL
Molecular Weight:: 60-75 kDa
Purity:: ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
Storage Conditions:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Immunogen:: Phe21-Gly467
Formulation:: Recombinant Human MMP-8 Protein is expressed from Expi293 with His tag at the C-terminal.; It contains Phe21-Gly467.
Species:: Human
Sequence:: FPVSSKEKNTKTVQDYLEKFYQLPSNQYQSTRKNGTNVIVEKLKEMQRFFGLNVTGKPNEETLDMMKKPRCGVPDSGGFMLTPGNPKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFRETSNYSLPQDDIDGIQAIYGLSSNPIQPTGPSTPKPCDPSLTFDAITTLRGEILFFKDRYFWRRHPQLQRVEMNFISLFWPSLPTGIQAAYEDFDRDLIFLFKGNQYWALSGYDILQGYPKDISNYGFPSSVQAIDAAVFYRSKTYFFVNDQFWRYDNQRQFMEPGYPKSISGAFPGIESKVDAVFQQEHFFHVFSGPRYYAFDLIAQRVTRVARGNKWLNCRYG
Uniprot:: P22894
Synonyms:: CLG1;collagenase 2;HNC;matrix metalloproteinase 8 (neutrophil collagenase);matrix metalloproteinase-8;MMP-8;neutrophil collagenase;PMN leukocyte collagenase;PMNL collagenase;PMNL-CL
Extra Details:: Alteration of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) expression has been studied for various cardiac diseases, including dilated cardiomyopathy (DCM), with the significance of surrogate markers of extracellular matrix (ECM) remodeling. MMP-8 was identified only in myocardiocytes, while MMP-9 and TIMP-2 were present in both myocardiocytes and stroma, but with different intensity. The increasing intensity of MMP-8 and TIMP-2 immunoreactions was significantly associated with low HCS.

Shipping Conditions:: Blue Ice