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RP02612

Recombinant Mouse Interferon alpha/beta receptor 1/IFNAR1 Protein

Size

£395.00

SKU:
RP02612
Additional Names:
AVP|CRF2-1|IFN-alpha-REC|IFN-alpha/beta R1|IFN-aR1|IFN-R-1|IFNAR|IFNAR1|IFNBR|IFNbR1|IFRC
Molecular Weight:
83-110 kDa
Purity:
≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Immunogen:
Glu27-Thr429
Formulation:
Recombinant Mouse Interferon alpha/beta receptor 1/IFNAR1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu27-Thr429) of Mouse Interferon alpha/beta receptor 1/IFNAR1 (Accession #) fused with hFc tag at the C-terminal.
Species:
Mouse
Sequence:
ENLKPPENIDVYIIDDNYTLKWSSHGESMGSVTFSAEYRTKDEAKWLKVPECQHTTTTKCEFSLLDTNVYIKTQFRVRAEEGNSTSSWNEVDPFIPFYTAHMSPPEVRLEAEDKAILVHISPPGQDGNMWALEKPSFSYTIRIWQKSSSDKKTINSTYYVEKIPELLPETTYCLEVKAIHPSLKKHSNYSTVQCISTTVANKMPVPGNLQVDAQGKSYVLKWDYIASADVLFRAQWLPGYSKSSSGSRSDKWKPIPTCANVQTTHCVFSQDTVYTGTFFLHVQASEGNHTSFWSEEKFIDSQKHILPPPPVITVTAMSDTLLVYVNCQDSTCDGLNYEIIFWENTSNTKISMEKDGPEFTLKNLQPLTVYCVQARVLFRALLNKTSNFSEKLCEKTRPGSFST
Uniprot:
P33896
Synonyms:
I;If;Ifar;IFN-alpha/beta receptor 1;IFN-alpha/betaR;IFN-R-1;Ifnar;Ifrc;INF-a receptor;Infar;interferon alpha/beta receptor 1;type I interferon receptor 1
Extra Details:
IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits of the different receptor complexes are shared and serve multiple functions.Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves.
Shipping Conditions:
Blue Ice