RP02600B
Biotinylated Recombinant Human TNFSF18/GITR Ligand Trimer Protein (Primary Amine Labeling)
Size
£657.00
- SKU:
- RP02600B
- Additional Names:
- AITRL|GITR Ligand|GITRL|TL6|TNFSF18
- Molecular Weight:
- 50-70 kDa
- Purity:
- ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Gln50-Ser177
- Formulation:
- Biotinylated Recombinant Human GITR Ligand/TNFSF18 Trimer Protein (Primary Amine Labeling) is expressed from Expi293 with His tag and flag tag at the N-terminal.; It contains Gln50-Ser177.
- Species:
- Human
- Uniprot:
- Q9UNG2
- Synonyms:
- activation-inducible TNF-related ligand;AITR ligand;AITRL;GITR ligand;GITRL;glucocorticoid-induced TNF-related ligand;glucocorticoid-induced TNFR-related protein ligand;hGITRL;TL6;TNLG2A;tumor necrosis factor (ligand) superfamily, member 18;tumor necrosis factor ligand 2A;tumor necrosis factor ligand superfamily member 18;tumor necrosis factor superfamily member 18
- Extra Details:
- Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept .
- Shipping Conditions:
- Blue Ice