RP02591B
Biotinylated Recombinant Human SIRP-beta 1/CD172b Protein
Size
£657.00
- SKU:
- RP02591B
- Additional Names:
- 9930027N05Rik|CD172b|DKFZp686A05192|FLJ26614|SIRP-beta|SIRP-beta-1 isoform 3|Sirpb|SIRPB1|Sirpb1a
- Molecular Weight:
- 55-68 kDa
- Purity:
- ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Glu30-Leu371
- Formulation:
- Biotinylated Recombinant Human SIRP-beta 1/CD172b Protein is produced by Expi293 expression system. The target protein is expressed with sequence ( Glu30-Leu371) of Human SIRP-beta 1/CD172b fused with His tag and Avi tag at the C-terminus.
- Species:
- Human
- Uniprot:
- Q5TFQ8-1
- Synonyms:
- CD172 antigen-like family member B;CD172b;signal-regulatory protein beta-1;SIRP-BETA-1
- Extra Details:
- Signal regulatory protein B Beta1 (SIRPB1) is a signal regulatory protein member of the immunoglobulin superfamily and is capable of modulating receptor tyrosine kinase-coupled signaling. Copy number variations at the SIRPB1 locus were previously reported to associate with prostate cancer aggressiveness in patients.SIRPB1 gene amplification and overexpression were detected in prostate cancer specimens. The knockdown of SIRPB1 significantly suppressed cell growth in colony formation assays and cell mobility.
- Shipping Conditions:
- Blue Ice