RP02464B
Biotinylated Recombinant Human Oncostatin-M/OSM Protein
Size
£657.00
- SKU:
- RP02464B
- Additional Names:
- OSM, oncostatin-M
- Molecular Weight:
- 30-40 kDa
- Purity:
- ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Ala26-Arg221
- Formulation:
- Biotinylated Recombinant Human Oncostatin-M/OSM Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Ala26-Arg221) of Human Oncostatin-M fused with a His tag and Avi tag at the C-terminal.
- Species:
- Human
- Uniprot:
- P13725
- Synonyms:
- oncostatin-M
- Extra Details:
- OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
- Shipping Conditions:
- Blue Ice