RP02386B
Biotinylated Recombinant Human IGF1R/CD221 Protein
Size
£657.00
- SKU:
- RP02386B
- Additional Names:
- IGF1R,CD221,IGFIR,IGFR,JTK13
- Molecular Weight:
- 110-120, 52-55 kDa
- Purity:
- ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Met1-Asn932
- Formulation:
- Biotinylated Recombinant Human IGF1R/CD221 Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Met1-Asn932 ) of Human IGF1R fused with a His tag and Avi tag at the C-terminal.
- Species:
- Human
- Uniprot:
- P08069
- Synonyms:
- CD221;IGF-I receptor;IGFIR;IGFR;insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;JTK13;soluble IGF1R variant 1;soluble IGF1R variant 2
- Extra Details:
- The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, protease secretion, tumour cell motility and adhesion, and thus can affect the propensity for invasion and metastasis. Therefore, the IGF1R is now an attractive anti-cancer treatment target.
- Shipping Conditions:
- Blue Ice