RP02357B
Biotinylated Recombinant Human FGFR-4/CD334 Protein
Size
£657.00
- SKU:
- RP02357B
- Additional Names:
- CD334, JTK2, TKF,FGFR4,JTK2,TKF
- Molecular Weight:
- 55-72 kDa
- Purity:
- ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Leu22-Asp369
- Formulation:
- Biotinylated Recombinant Human FGFR-4/CD334 Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Leu22-Asp369) of Human FGFR4 fused with a His tag and Avi tag at the C-terminal.
- Species:
- Human
- Uniprot:
- P22455
- Synonyms:
- CD334;fibroblast growth factor receptor 4;hydroxyaryl-protein kinase;JTK2;protein-tyrosine kinase;TKF;tyrosine kinase related to fibroblast growth factor receptor;tyrosylprotein kinase
- Extra Details:
- Fibroblast growth factor receptor 4 (FGF R4), also known as CD334, is a 110 kDa glycosylated transmembrane receptor tyrosine kinase.Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19.
- Shipping Conditions:
- Blue Ice