RP02276B
Biotinylated Recombinant Human Tyrosine-protein kinase receptor UFO/Axl Protein
Size
£558.45
Was £657.00
- SKU:
- RP02276B
- Additional Names:
- AXL,ARK,JTK11,Tyro7,UFO
- Molecular Weight:
- 70-80 kDa
- Purity:
- ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Ala26-Pro449
- Formulation:
- Biotinylated Recombinant Human Tyrosine-protein kinase receptor UFO/Axl Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Ala26-Pro449) of Human Axl fused with a His and Avi tag at the C-terminal.
- Species:
- Human
- Uniprot:
- P30530
- Synonyms:
- ARK;AXL oncogene;AXL transforming sequence/gene;JTK11;Tyro7;tyrosine-protein kinase receptor UFO;UFO
- Extra Details:
- Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers.
- Shipping Conditions:
- Blue Ice