RP02186
Recombinant Human IGF2BP2 Protein
Size
£193.00
- SKU:
- RP02186
- Additional Names:
- IGF2BP2,IMP-2,IMP2,VICKZ2, IMP2, VICKZ2
- Molecular Weight:
- 29 kDa
- Purity:
- ≥ 80 %
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Met1-Thr220
- Formulation:
- Recombinant Human IGF2BP2 Protein is produced by E.coli expression system. The target protein is expressed with sequence (Met1-Thr220) of human IGF2BP-2 (Accession #Q9Y6M1) fused with a T7 tag at the N-terminus and a 6xHis tag at the C-terminus.
- Species:
- Human
- Uniprot:
- Q9Y6M1
- Synonyms:
- Hepatocellular carcinoma autoantigen p62;IGF-II mRNA-binding protein 2;IGF2 mRNA-binding protein 2;IMP-2;IMP2;insulin-like growth factor 2 mRNA-binding protein 2;VICKZ family member 2;VICKZ2
- Extra Details:
- Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replication analyses.
- Shipping Conditions:
- Blue Ice