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RP02149

Recombinant Human Cyclophilin B/PPIase B/PPIB Protein

Size

£145.00

SKU:
RP02149
Additional Names:
CYP-S1, CYPB, HEL-S-39, OI9, SCYLP,PPIB, CYP-S1, peptidylprolyl isomerase B,CYPB,HEL-S-39,OI9,SCYLP
Molecular Weight:
21 kDa
Purity:
≥95%
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Immunogen:
Asp34-Ala212
Formulation:
Recombinant Human Cyclophilin B/PPIase B/PPIB Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Asp34-Ala212) of human PPIB (Accession #P23284) fused with a 6xHis tag at the C- terminus.
Species:
Human
Sequence:
DEKKKGPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADCGKIEVEKPFA
Uniprot:
P23284
Synonyms:
B;Cyclophilin B;cyclophilin-like protein;CYP-S1;CYPB;epididymis secretory protein Li 39;HEL-S-39;OI9;peptidyl-prolyl cis-trans isomerase B;peptidylprolyl isomerase B (cyclophilin B);PPIase B;rotamase B;S-cyclophilin;SCYLP
Extra Details:
Cyclophilin B (SCYLP, CyPB and peptidyl-prolyl cis-trans isomerase B) is a 24 kDa glycoprotein member of the B subfamily of the cyclophilin-type PPIase family of molecules. It is both secreted and retained in the ER. When secreted, Cyclophilin B mediates chemotaxis and T cell adhesion to fibronectin. This is likely due to its prolyl cis/trans isomerase activity. Intracellularly, Cyclophilin B appears to serve as a molecular chaperone for molecules destined for secretion. It does so via stabilization, and facilitating the activity of additional chaperones.
Shipping Conditions:
Blue Ice