RP02081B
Biotinylated Recombinant Human TNF-alpha Protein
Size
£657.00
- SKU:
- RP02081B
- Additional Names:
- TNF, DIF, TNF-alpha, TNFA, TNFSF2, TNLG1F, tumor necrosis factor,TNF-A Alpha,DIF,TNF-alpha,TNFA,TNFSF2,TNLG1F,TNF alpha
- Molecular Weight:
- 21-24 kDa
- Purity:
- ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Val77-Leu233
- Formulation:
- Biotinylated Recombinant Human TNF-alpha Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Val77-Leu233 ) of Human TNF-alpha fused with a His and Avi tag at the C-terminal.
- Species:
- Human
- Uniprot:
- P01375
- Synonyms:
- APC1 protein;Cachectin;DIF;TNF-a;TNF-alpha;TNF, macrophage-derived;TNF, monocyte-derived;TNFA;TNFSF2;TNLG1F;tumor necrosis factor;tumor necrosis factor ligand 1F;tumor necrosis factor ligand superfamily member 2;tumor necrosis factor-alpha
- Extra Details:
- Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism.Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.
- Shipping Conditions:
- Blue Ice