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RP02061

Recombinant Cynomolgus CD3E&CD3D Protein

Size

£508.00

SKU:
RP02061
Additional Names:
CD3 epsilon&CD3 delta|CD3E&CD3D
Molecular Weight:
58-62 kDa (CD3E), 44-46 kDa (CD3D)
Purity:
≥ 95 % as determined by SDS-PAGE;≥95 %
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Immunogen:
Gln22-Asp117(Q95LI52)&Phe22-Ala105(Q95LI8)
Formulation:
Recombinant Cynomolgus CD3E&CD3G Protein is produced by mammalian expression system. The target protein is expressed with sequence (Asp20-Arg687 (Q95LI52) & Phe22-Ala105 (Q95LI8) ) of cynomolgus CD3E&CD3D (Accession #Q95LI5.2 & Q95LI8) fused with an Fc tag at the C-terminus.
Species:
Non-human Primate
Sequence:
QDGNEEMGSITQTPYQVSISGTTVILTCSQHLGSEAQWQHNGKNKEDSGDRLFLPEFSEMEQSGYYVCYPRGSNPEDASHHLYLKARVCENCMEMDFKIPVEELEDRVFVKCNTSVTWVEGTVGTLLTNNTRLDLGKRILDPRGIYRCNGTDIYKDKESAVQVHYRMCQNCVELDPATLA
Uniprot:
Q95LI5.2, Q95LI8
Synonyms:
CD3 delta;CD3 epsilon FN18-;CD3 epsilon FN18+;CD3d molecule, delta (CD3-TCR complex);CD3e molecule, epsilon (CD3-TCR complex);T-cell receptor T3 delta chain;T-cell surface glycoprotein CD3 delta chain;T-cell surface glycoprotein CD3 epsilon chain
Extra Details:
T-cell surface glycoprotein CD3 epsilon & CD3 delta chain, also known as CD3E & CD3D , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.
Shipping Conditions:
Blue Ice