Recombinant Human TNF-beta Protein

Size

£133.00

SKU:: RP01977
Additional Names:: LTA, TNFB, TNFSF1,Lymphotoxin-alpha, LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1
Molecular Weight:: 20-25 kDa
Purity:: ≥95%
Storage Conditions:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Immunogen:: Leu35-Leu205
Formulation:: Recombinant Human TNF-beta Protein is produced by CHO Cells expression system. The target protein is expressed with sequence (Leu35-Leu205) of Human TNF-beta(Accession #NP_000586.2) fused with His at the C-terminus.
Species:: Human
Sequence:: LPGVGLTPSAAQTARQHPKMHLAHSTLKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLSNNSLLVPTSGIYFVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLLSSQKMVYPGLQEPWLHSMYHGAAFQLTQGDQLSTHTDGIPHLVLSPSTVFFGAFAL
Uniprot:: P01374
Synonyms:: LT;LT-alpha;lymphotoxin-alpha;TNF superfamily, member 1;TNF-beta;TNFB;TNFSF1;TNLG1E;truncated lymphotoxin alpha;tumor necrosis factor beta;tumor necrosis factor ligand 1E;tumor necrosis factor ligand superfamily member 1
Extra Details:: Tumor Necrosis Factor B Beta (TNF- B Beta ) is a secreted protein belonging to the tumor necrosis factor family. TNF- B Betabinds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM in homotrimeric form, binds toTNFRSF3/LTBR in heterotrimeric form with LTB. TNF- B Beta forms heterotrimers with lymphotoxin-beta, whichanchors TNF- B Beta to the cell surface. TNF- B Beta mediates the inflammatory, immunostimulatory, and antiviralresponse, involves in the formation of second lymphoid organs during development, has a role in apoptosis.TNF-B Beta is produced by lymphocytes and cytotoxic for a variety of tumor cells in vitro and in vivo.

Shipping Conditions:: Blue Ice