RP01969
Recombinant Human MMP-10 Protein
Size
£145.00
- SKU:
- RP01969
- Additional Names:
- MMP10, STMY2,Stromelysin-2, SL-2, EC:3.4.24.22, Matrix metalloproteinase-10, MMP-10, Transin-2
- Molecular Weight:
- 45-60,60-65 kDa
- Purity:
- ≥95%
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Tyr18-Cys476
- Formulation:
- Recombinant Human MMP-10 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Tyr18-Cys476) of Human MMP-10 (Accession #NP_002416.1) fused with His at the C-terminus.
- Species:
- Human
- Sequence:
- YPLSGAAKEEDSNKDLAQQYLEKYYNLEKDVKQFRRKDSNLIVKKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSFPGMPKWRKTHLTYRIVNYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGPGHSLAHAYPPGPGLYGDIHFDDDEKWTEDASGTNLFLVAAHELGHSLGLFHSANTEALMYPLYNSFTELAQFRLSQDDVNGIQSLYGPPPASTEEPLVPTKSVPSGSEMPAKCDPALSFDAISTLRGEYLFFKDRYFWRRSHWNPEPEFHLISAFWPSLPSYLDAAYEVNSRDTVFIFKGNEFWAIRGNEVQAGYPRGIHTLGFPPTIRKIDAAVSDKEKKKTYFFAADKYWRFDENSQSMEQGFPRLIADDFPGVEPKVDAVLQAFGFFYFFSGSSQFEFDPNARMVTHILKSNSWLHC
- Uniprot:
- P09238
- Synonyms:
- matrix metalloprotease 10;matrix metalloproteinase 10 (stromelysin 2);matrix metalloproteinase-10;MMP-10;SL-2;STMY2;stromelysin-2;transin 2;Transin-2
- Extra Details:
- Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-10 degrades a broad range of substrates including gelatin, collagen types III, IV and V, fibronectin, aggrecan, and pig cartilage proteoglycan. MMP-10 can activate other MMPs such as MMP-1 and MMP-8. MMP-10 is expressed in keratinocytes, T cells, menstrual endometrium and a few tumor samples. Structurally, MMP-10 may be divided into four distinct domains: a pro-domain which is cleaved upon activation, a catalytic domain containing the zinc binding site; a short linker region, and a carboxyl terminal hemopexin-like domain.
- Shipping Conditions:
- Blue Ice