Recombinant Rat IL-4 Protein

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£193.00

SKU:: RP01874
Additional Names:: B-cell growth factor 1|B-cell IGG differentiation factor|B-cell stimulatory factor 1|BSF-1|H-IL-4|IL-4|ILN|Interleukin|Interleukin-4|Interleukin4|Lymphocyte stimulatory factor 1|M-IL-4|MGC79402
Molecular Weight:: 15-25 kDa
Purity:: ≥90%
Storage Conditions:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Immunogen:: Cys25-Ser147
Formulation:: Recombinant Rat IL-4 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Cys25-Ser147) of Rat IL-4 (Accession #NP_958427.1) fused with a His at the C-terminus.
Species:: Rat
Sequence:: CNDSPLREIINTLNQVTEKGTPCTEMFVPDVLTATRNTTENELICRASRVLRKFYFPRDVPPCLKNKSGVLGELRKLCRGVSGLNSLRSCTVNESTLTTLKDFLESLKSILRGKYLQSCTSMS
Uniprot:: P20096
Synonyms:: B-cell growth factor 1;B-cell IGG differentiation factor;B-cell stimulatory factor 1;BSF-1;IL-4;Il4e12;interleukin-4;lymphocyte stimulatory factor 1
Extra Details:: Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.

Shipping Conditions:: Blue Ice