RP01854
Recombinant Human ApolipoproteinA-IV/APOA4 Protein
Size
£145.00
- SKU:
- RP01854
- Additional Names:
- APOA4, Apolipoprotein A-IV, Apo-AIV, ApoA-IV, Apolipoprotein A4.
- Molecular Weight:
- 45-55 kDa
- Purity:
- ≥90%
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Glu21-Ser396
- Formulation:
- Recombinant Human Apolipoprotein A-IV/APOA4 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu21-Ser396) ofHuman Apolipoprotein A-IV/APOA4 (Accession #NP_000473.2) fused with a His tag at the C-terminus.
- Species:
- Human
- Sequence:
- EVSADQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEVNTYAGDLQKKLVPFATELHERLAKDSEKLKEEIGKELEELRARLLPHANEVSQKIGDNLRELQQRLEPYADQLRTQVSTQAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKVNSFFSTFKEKESQDKTLSLPELEQQQEQQQEQQQEQVQMLAPLES
- Uniprot:
- P06727
- Synonyms:
- apo-AIV;apoA-IV;apolipoprotein A-IV;Apolipoprotein A4
- Extra Details:
- Apolipoprotein A-IV (ApoA-IV), first discovered in rat plasma in the 1970s , is a 46 kD glycoprotein with relatively high concentrations in plasma (15-37 mg/dL) . It is expressed predominantly in the mammalian small intestine (with highest expression in the duodenum), and also expressed in rodent liver at lower levels. Sensing lipid absorption in enterocytes , ApoA-IV is synthesized and packaged with lipids and other apolipoproteins into chylomicrons and secreted through the lymphatic system into the blood. Once there, as a member of exchangeable apolipoproteins, ApoA-IV dissociates from chylomicrons and transfers to HDL (high density lipoprotein) particles or circulates in lipid-free form .ApoA-IV may protect against atherosclerosis , mediate reverse cholesterol transport , act as an anti-inflammatory agent and modulate intestinal lipid absorption .
- Shipping Conditions:
- Blue Ice