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RP01821

Recombinant Human FSH Beta Protein

Size

£163.00

SKU:
RP01821
Additional Names:
FSH Beta|FSHB|HH24
Molecular Weight:
20-25 kDa
Purity:
≥95%
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Immunogen:
Asn19-Glu129
Formulation:
Recombinant Human FSH Beta Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asn19-Glu129) of human FSH Beta (Accession #NP_000501.1) fused with a 6xHis tag at the C-terminus.
Species:
Human
Sequence:
NSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVYKDPARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVRGLGPSYCSFGEMKE
Uniprot:
P01225
Synonyms:
follicle stimulating hormone beta subunit;follicle stimulating hormone, beta polypeptide;Follicle-stimulating hormone beta subunit;Follitropin beta chain;follitropin subunit beta;follitropin, beta chain;FSH-B;FSH-beta;HH24
Extra Details:
Follicle-stimulating hormone (FSH) is a gonadotrope-derived heterodimeric glycoprotein. FSH plays an essential role in processes involved in human reproduction, including spermatogenesis and the ovarian cycle. FSHB represents a conservative vertebrate gene with a unique function and it is located in a structurally stable gene-poor region. Polymorphisms in the follicle stimulating hormone beta subunit (FSHB) and follicle stimulating hormone receptor (FSHR) genes might disturb normal spermatogenesis and affect male reproductive ability. The FSHB -211G>T genotype is a key determinant in the regulation of gonadotropins in different reproductive-endocrine pathopyhsiologies.
Shipping Conditions:
Blue Ice