Recombinant Human IL1RAPL-2 Protein

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£145.00

SKU:: RP01820
Additional Names:: IL-1R9|IL1R9|IL1RAPL-2|IL1RAPL2|TIGIRR-1
Molecular Weight:: 75-100 kDa
Purity:: ≥95%
Storage Conditions:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Immunogen:: Thr17-Glu356
Formulation:: Recombinant Human IL1RAPL-2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Thr17-Glu356) of human IL1RAPL-2 (Accession #NP_059112.1) fused with hFc and 6xHis tag at the C-terminus.
Species:: Human
Sequence:: TNLKMVSKRNSVDGCIDWSVDLKTYMALAGEPVRVKCALFYSYIRTNYSTAQSTGLRLMWYKNKGDLEEPIIFSEVRMSKEEDSIWFHSAEAQDSGFYTCVLRNSTYCMKVSMSLTVAENESGLCYNSRIRYLEKSEVTKRKEISCPDMDDFKKSDQEPDVVWYKECKPKMWRSIIIQKGNALLIQEVQEEDGGNYTCELKYEGKLVRRTTELKVTALLTDKPPKPLFPMENQPSVIDVQLGKPLNIPCKAFFGFSGESGPMIYWMKGEKFIEELAGHIREGEIRLLKEHLGEKEVELALIFDSVVEADLANYTCHVENRNGRKHASVLLRKKDLIYKIE
Uniprot:: Q9NP60
Synonyms:: IL-1 receptor accessory protein-like 2;IL-1R-9;IL-1R9;IL1R9;IL1RAPL-2;IL1RAPL-2-related protein;interleukin 1 receptor 9;Interleukin-1 receptor 9;three immunoglobulin domain-containing IL-1 receptor-related 1;TIGIRR-1;X-linked interleukin-1 receptor accessory protein-like 2
Extra Details:: X-linked interleukin-1 receptor accessory protein-like 2 (IL1RAPL2) or Interleukin-1 receptor 9 (IL-1R9) is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins. IL-1R9/IL1RAPL2 shows restricted expression in the fetal brain and is highly homologous to IL1RAPL, which is reportedly involved in nonsyndromic X-linked mental retardation. IL-1R9/IL1RAPL2 is highly homologous to IL-1R8. Both forms have no known ligands and receptors are found in the fetal brain. IL-1R9/IL1RAPL2 may function as a negative receptor. Both IL1RAPL1 and IL1RAPL2 have novel C-terminal sequences not present in other related proteins. IL-1R9/IL1RAPL2 may be strong candidates for X-linked non-syndromic mental retardation loci, and that molecules resembling IL-1 and IL-18 play a role in the development or function of the central nervous system.

Shipping Conditions:: Blue Ice