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RP01814

Recombinant Human Neurogranin/NRGN Protein

Size

£133.00

SKU:
RP01814
Additional Names:
hng|Neurogranin|NRGN|RC3
Molecular Weight:
45 kDa
Purity:
≥95%
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Immunogen:
Asp2-Asp78
Formulation:
Recombinant Human Neurogranin/NRGN Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp2-Asp78) of human NRGN/Neurogranin (Accession #) fused with hFc tag at the C-terminus.
Species:
Human
Sequence:
DCCTENACSKPDDDILDIPLDDPGANAAAAKIQASFRGHMARKKIKSGERGRKGPGPGGPGGAGVARGGAGGGPSGD
Uniprot:
Q92686
Synonyms:
calmodulin-binding protein;hng;neurogranin;neurogranin (protein kinase C substrate, RC3);protein kinase C substrate;RC3
Extra Details:
Neurogranin is as a small protein encoded by the NRGN gene. it is a calmodulin-binding protein expressed primarily in the brain, particularly in dendritic spines, and participating in the protein kinase C signaling pathway. Neurogranin is the main postsynaptic protein regulating the availability of calmodulin, binding to it in the absence of calcium. Phosphorylation by protein kinase C lowers its binding ability. It is a potential biomarker of neurological and mental diseases.
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Blue Ice