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RP01780

Recombinant Human TGF-alpha Protein

Size

£133.00

SKU:
RP01780
Additional Names:
TFGA|TGF-alpha
Molecular Weight:
10-15 kDa
Purity:
≥90%
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Immunogen:
Val40-Ala89
Formulation:
Recombinant Human TGF-alpha Protein is produced by E. coli expression system. The target protein is expressed with sequence (Val40-Ala89) of human TGF-alpha/TGFA (Accession #NP_003227.1) fused with no tag.
Species:
Human
Sequence:
VVSHFNDCPDSHTQFCFHGTCRFLVQEDKPACVCHSGYVGARCEHADLLA
Uniprot:
P01135-1
Synonyms:
protransforming growth factor alpha;TFGA;TGF-alpha
Extra Details:
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared to adjacent normal tissue and high TGFA gene expression strongly correlated with poor survival in patients with lung adenocarcinoma, and miR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression. Transforming growth factor alpha (TGFA) is a well-characterized mammalian growth factor that might contribute to the development of Cleft lip and palate (CL/P).
Shipping Conditions:
Blue Ice