Recombinant Human Calcitonin/CALCA Protein

Size

£145.00

SKU:: RP01728
Additional Names:: CALC1|CALCA|CGRP|CGRP-alpha|CGRP-I|CGRP1|CT|KC|PCT|Procalcitonin
Molecular Weight:: 14-20 kDa
Purity:: ≥90%
Storage Conditions:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Immunogen:: Ala26-Asn141
Formulation:: Recombinant Human Calcitonin/CALCA Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala26-Asn141) of human Calcitonin/CALCA (Accession #NP_001029124.1) fused with and a 6xHis tag at the C-terminus.
Species:: Human
Sequence:: APFRSALESSPADPATLSEDEARLLLAALVQDYVQMKASELEQEQEREGSSLDSPRSKRCGNLSTCMLGTYTQDFNKFHTFPQTAIGVGAPGKKRDMSSDLERDHRPHVSMPQNAN
Uniprot:: P01258-1
Synonyms:: alpha-type CGRP;CALC1;calcitonin;calcitonin 1;calcitonin gene-related peptide 1;calcitonin gene-related peptide I;calcitonin/calcitonin-related polypeptide, alpha;CGRP;CGRP-alpha;CGRP-I;CGRP1;CT;katacalcin;KC;PCT
Extra Details:: This protein is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

Shipping Conditions:: Blue Ice