Recombinant Mouse FGF-21 Protein

Size

£133.00

SKU:: RP01715
Additional Names:: FGF21|Fgf8c
Molecular Weight:: 20-25 kDa
Purity:: ≥95%
Storage Conditions:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Immunogen:: Tyr30-Ser210
Formulation:: Recombinant Mouse FGF-21 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Tyr30-Ser210) of mouse FGF-21 (Accession #NP_064397.1.) fused with and a 6xHis tag at the C-terminus.
Species:: Mouse
Sequence:: YPIPDSSPLLQFGGQVRQRYLYTDDDQDTEAHLEIREDGTVVGAAHRSPESLLELKALKPGVIQILGVKASRFLCQQPDGALYGSPHFDPEACSFRELLLEDGYNVYQSEAHGLPLRLPQKDSPNQDATSWGPVRFLPMPGLLHEPQDQAGFLPPEPPDVGSSDPLSMVEPLQGRSPSYAS
Uniprot:: Q9JJN1
Synonyms:: Fgf8c;fibroblast growth factor 21;fibroblast growth factor 8c
Extra Details:: Fibroblast growth factor 21 (FGF21), which stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression. FGF21 has been shown to protect animals from diet-induced obesity when overexpressed in transgenic mice. It also lowers blood glucose and triglyceride levels when administered to diabetic rodents, suggesting it may exhibit the therapeutic characteristics necessary for effective treatment of diabetes. Treatment of animals with FGF21 results in increased energy expenditure, fat utilisation and lipid excretion. FGF21 is most abundantly expressed in the liver, and also expressed in the thymus at lower levels.

Shipping Conditions:: Blue Ice