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RP01650

Recombinant Human IFN-gamma R2 Protein

Size

£133.00

SKU:
RP01650
Additional Names:
AF-1|IFGR2|IFNGR2|IFNGT1|IMD28
Molecular Weight:
65-75 kDa
Purity:
≥95%
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Immunogen:
Ser28-Asp240
Formulation:
Recombinant Human IFN-gamma R2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser28-Asp240) of human IFN-gamma R2 (Accession #NP_005525.2) fused with and a RaFc tag at the C-terminus.
Species:
Human
Sequence:
SQLPAPQHPKIRLYNAEQVLSWEPVALSNSTRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRAELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAFFCYYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKSNIFRVGHLSNISCYETMAD
Uniprot:
P38484
Synonyms:
AF-1;IFGR2;IFN-gamma receptor 2;IFN-gamma-R-beta;IFN-gamma-R2;IFNGT1;IMD28;interferon gamma receptor 2;Interferon gamma receptor accessory factor 1;interferon gamma receptor accessory factor-1;interferon gamma receptor beta chain;Interferon gamma receptor beta-chain;interferon gamma transducer 1
Extra Details:
Interferon-gamma receptor beta chain (IFNgammaR2), also known as IFNGR2, belongs to the type II cytokine receptor family, whose deficiency is a cause of autosomal recessive mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. This accessory factor is an integral part of the IFN-gamma signal transduction pathway and is likely to interact with GAF, JAK1, and/or JAK2.
Shipping Conditions:
Blue Ice