RP01618SLQ
Recombinant Human Wnt-3a Surrogate Protein
Size
£163.00
- SKU:
- RP01618SLQ
- Additional Names:
- WNT3A,Protein Wnt-3a,Wnt3a Surrogate
- Molecular Weight:
- 66-75 kDa
- Purity:
- ≥ 95 % as determined by SDS-PAGE;≥ 95%
- Storage Conditions:
- -70[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Wnt Surrogate Protein
- Formulation:
- Recombinant Human Wnt-3a Surrogate Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence of Human Wnt-3a Surrogate fused with hFC at the C-terminus.
- Species:
- Human
- Extra Details:
- Wnt3a Surrogate protein is a Wnt recombination protein that plays an important role in embryonic development, adult tissue homeostasis and injury repair. Wnt3a Surrogate protein, consisting of the domain and Fc portion of Wnt3a, helps organoids expand and maintain a source of Wnt. Organoids are a rapidly evolving model system for tissue development, and Wnt3a is considered as the essential protein for organoid growth. Wnt3a or the small molecule glycogen synthase kinase 3 (GSK3) inhibitor CHIR are commonly used as Wnt sources in experiments. However, the application of Wnt3a is hampered by Wnt lipidation, and cross-reactivity with Wnt frizzled (Fzd). Therefore, Wnt3a Surrogate protein was used instead of Wnt3a, as a water-soluble and Fzd-specific alternative Wnt agonist.
- Shipping Conditions:
- Dry Ice