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RP01565

Recombinant Mouse CD52 Protein

Size

£133.00

SKU:
RP01565
Additional Names:
CDW52,HE5,CD52,CAMPATH-1 antigen,CD52
Molecular Weight:
35-45 kDa
Purity:
≥95%
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Immunogen:
Gly24-Ser47
Formulation:
Recombinant Mouse CD52 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly24-Ser47) of mouse CD52 (Accession #NP_038734.1) fused with a hFc tag at the C-terminus.
Species:
Mouse
Sequence:
GQATTAASGTNKNSTSTKKTPLKS
Uniprot:
Q64389
Synonyms:
AI463198;B7;B7-Ag;CAMPAT;CAMPATH-1;CAMPATH-1 antigen;CL;CLS1;lymphocyte differentiation antigen B7;MB7
Extra Details:
CD52/CDW52 is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein. It has a mature peptide comprising only 12 amino acids and is abundantly expressed on human lymphocytes. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.
Shipping Conditions:
Blue Ice