Recombinant Human WAIF1/5T4/TPBG Protein

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£145.00

SKU:: RP01445
Additional Names:: 5T4, 5T4AG, M6P1, WAIF1,TPBG,5T4AG,M6P1,WAIF1
Molecular Weight:: 55-70 kDa
Purity:: ≥95%
Storage Conditions:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Immunogen:: Ser32-Ser355
Formulation:: Recombinant Human WAIF1/5T4/TPBG Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser32-Ser355) of human TPBG/5T4 (Accession #NP_006661.1) fused with a 6xHis tag at the C-terminus.
Species:: Human
Sequence:: SSPTSSASSFSSSAPFLASAVSAQPPLPDQCPALCECSEAARTVKCVNRNLTEVPTDLPAYVRNLFLTGNQLAVLPAGAFARRPPLAELAALNLSGSRLDEVRAGAFEHLPSLRQLDLSHNPLADLSPFAFSGSNASVSAPSPLVELILNHIVPPEDERQNRSFEGMVVAALLAGRALQGLRRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLTYVSFRNLTHLESLHLEDNALKVLHNGTLAELQGLPHIRVFLDNNPWVCDCHMADMVTWLKETEVVQGKDRLTCAYPEKMRNRVLLELNSADLDCDPILPPSLQTS
Uniprot:: Q13641-1
Synonyms:: 5T4;5T4 oncofetal antigen;5T4 oncofetal trophoblast glycoprotein;5T4 oncotrophoblast glycoprotein;5T4AG;M6P1;trophoblast glycoprotein;WAIF1;wnt-activated inhibitory factor 1
Extra Details:: This protein is a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein.

Shipping Conditions:: Blue Ice