Recombinant Human CD52 Protein

Size

£145.00

SKU:: RP01429
Additional Names:: CD52,CDW52,EDDM5
Molecular Weight:: Approximately 40 kDa
Purity:: ≥95%
Storage Conditions:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Immunogen:: Gly25-Ser36
Formulation:: Recombinant Human CD52 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly25-Ser36) of human CD52 (Accession #NP_001794.2) fused with a Fc, Avi tag at the C-terminus.
Species:: Human
Sequence:: GQNDTSQTSSPS
Uniprot:: P31358
Synonyms:: cambridge pathology 1 antigen;CAMPATH-1 antigen;CD52 antigen (CAMPATH-1 antigen);CDW52;CDW52 antigen (CAMPATH-1 antigen);EDDM5;epididymal secretory protein E5;epididymis secretory sperm binding protein Li 171mP;HE5;HEL-S-171mP;human epididymis-specific protein 5
Extra Details:: CD52 / CDW52 is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein. It has a mature peptide comprising only 12 amino acids and is abundantly expressed on human lymphocytes. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.