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RP01039

Recombinant Human IL-2 Protein

Size

£133.00

SKU:
RP01039
Additional Names:
IL2,IL-2,TCGF,lymphokine
Molecular Weight:
16 kDa, 18 kDa
Purity:
≥95%
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Immunogen:
Ala21-Thr153
Formulation:
Recombinant Human IL-2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala21-Thr153) of human IL2 (Accession #NP_000577.2) fused with a 6xHis tag at the C-terminus.
Species:
Human
Sequence:
APTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
Uniprot:
P60568
Synonyms:
aldesleukin;IL-2;interleukin-2;involved in regulation of T-cell clonal expansion;lymphokine;T cell growth factor;T-cell growth factor;TCGF
Extra Details:
The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
Shipping Conditions:
Blue Ice