RP00552
Recombinant Human CD38 Protein
Size
£395.00
- SKU:
- RP00552
- Additional Names:
- ADP-ribosyl cyclase 1|ADPRC 1|cADPr hydrolase 1|CD38|CD38 molecule|EC 2.4.99.20|EC 3.2.2.6|T10
- Molecular Weight:
- 60-70 kDa
- Purity:
- ≥ 95 % as determined by SDS-PAGE;≥ 95 %
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Val43-Ile300
- Formulation:
- Recombinant Human CD38 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val43-Ile300) of Human CD38 (Accession #P28907-1) fused with a C-hFc tag at the C-terminus.
- Species:
- Human
- Sequence:
- VPRWRQQWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWDAFKGAFISKHPCNITEEDYQPLMKLGTQTVPCNKILLWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFNTSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVMLNGSRSKIFDKNSTFGSVEVHNLQPEKVQTLEAWVIHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPEDSSCTSEI
- Uniprot:
- P28907-1
- Synonyms:
- 2'-phospho-ADP-ribosyl cyclase;2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase;2'-phospho-cyclic-ADP-ribose transferase;ADP-ribosyl cyclase 1;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1;ADPRC 1;ADPRC1;CD38 antigen (p45);cluster of differentiation 38;cyclic ADP-ribose hydrolase 1;ecto-nicotinamide adenine dinucleotide glycohydrolase;NAD(+) nucleosidase;T10
- Extra Details:
- CD38 is highly and uniformly expressed on multiple myeloma (MM) cells, and at relatively low levels on normal lymphoid and myeloid cells, and in some tissues of nonhematopoietic origin. CD38 is a transmembrane glycoprotein with ectoenzymatic activity, and also functions as a receptor and adhesion molecule. Altogether, this has triggered the development of several CD38 antibodies including daratumumab (fully human), isatuximab (chimeric), and MOR202 (fully human).
- Shipping Conditions:
- Blue Ice