Biotinylated Recombinant Human FGFR-3 beta (IIIb)/CD333 Protein

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£657.00

SKU:: RP00462B
Additional Names:: ACH|CD333|CEK|CEK2|EC 2.7.10|FGF R3|FGFR3|HSFGFR3EX|JTK4
Molecular Weight:: 40-55 kDa
Purity:: ≥ 95 % as determined by SDS-PAGE;≥ 95 %
Storage Conditions:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Immunogen:: Asp127-Gly377
Formulation:: Biotinylated Recombinant Human FGFR-3 beta (IIIb)/CD333 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp127-Gly377) of Human FGFR3 beta (IIIb) (Accession #P22607-2) fused with a C-His&Avi tag at the C-terminus.
Species:: Human
Sequence:: DAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKSWISESVEADVRLRLANVSERDGGEYLCRATNFIGVAEKAFWLSVHGPRAAEEELVEADEAGSVYAG
Uniprot:: P22607-2
Synonyms:: ACH;CD333;CEK2;FGFR-3;fibroblast growth factor receptor 3;fibroblast growth factor receptor 3 variant 4;fibroblast growth factor receptor 3-S;HSFGFR3EX;hydroxyaryl-protein kinase;JTK4;tyrosine kinase JTK4
Extra Details:: Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid?box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis.

Shipping Conditions:: Blue Ice