Recombinant Human IL-2 R beta/CD122 Protein

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£395.00

SKU:: RP00448
Additional Names:: CD122|IL-15 R beta|IL-15 R B Beta|IL-2 R beta|IL-2 R B Beta|IL-2R subunit beta|IL-2R subunit B Beta|IL2RB|P70-75|p75|RP5-1170K4.6
Molecular Weight:: 60-70 kDa
Purity:: ≥ 95 % as determined by SDS-PAGE;≥ 95 %
Storage Conditions:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Immunogen:: Ala27-Asp239
Formulation:: Recombinant Human IL-2 R beta/CD122 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala27-Asp239) of Human IL-2 R beta/CD122 (Accession #P14784) fused with a C-hFc tag at the C-terminus.
Species:: Human
Sequence:: AVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPAALGKD
Uniprot:: P14784
Synonyms:: CD122;CD122 antigen;high affinity IL-2 receptor beta subunit;high affinity IL-2 receptor subunit beta;IL-2 receptor subunit beta;IL-2R subunit beta;IL-2RB;IL15RB;IMD63;interleukin 15 receptor, beta;interleukin 2 receptor, beta;interleukin-15 receptor subunit beta;interleukin-2 receptor subunit beta;P70-75;p75
Extra Details:: IL-2 R beta is a member of the cytokine receptor superfamily. Human IL-2 R beta cDNA encodes a 551 amino acid residue precursor Type I membrane protein with a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. Functional IL-2 receptors can exist in two affinity states on cell surfaces, the high affinity complex consisting of heterotrimers of the alpha, beta, and gamma chains, and the intermediate affinity complex comprising heterodimers of the beta and gamma chains.

Shipping Conditions:: Blue Ice