Biotinylated Recombinant Human Siglec-5/CD170 Protein (Primary Amine Labeling)

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£657.00

SKU:: RP00358B
Additional Names:: CD170|CD33 antigen-like 2|CD33L2|OB-BP2|OBBP2|Siglec5
Molecular Weight:: 90-115 kDa
Purity:: ≥95%
Storage Conditions:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Immunogen:: Glu17-Thr434
Formulation:: Biotinylated Recombinant Human Siglec-5/CD170 Protein (Primary Amine Labeling) is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu17-Thr434) of Human Siglec-5/CD170 (Primary Amine Labeling) (Accession #O15389) fused with a C-hFc tag at the C-terminus.
Species:: Human
Sequence:: EKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQMKRQGAQVTTERTVQLNVSYAPQTITIFRNGIALEILQNTSYLPVLEGQALRLLCDAPSNPPAHLSWFQGSPALNATPISNTGILELRRVRSAEEGGFTCRAQHPLGFLQIFLNLSVYSLPQLLGPSCSWEAEGLHCRCSFRARPAPSLCWRLEEKPLEGNSSQGSFKVNSSSAGPWANSSLILHGGLSSDLKVSCKAWNIYGSQSGSVLLLQGRSNLGT
Uniprot:: O15389
Synonyms:: CD170;CD33 antigen-like 2;CD33L2;OB-binding protein 2;OB-BP2;OBBP2;obesity-binding protein 2;sialic acid-binding Ig-like lectin 5;sialic acid-binding immunoglobulin-like lectin 5;SIGLEC-5
Extra Details:: Group B Streptococcus (GBS) causes invasive infections in human newborns. the GBS B Beta-protein attenuates innate immune responses by binding to sialic acid-binding immunoglobulin-like lectin 5 (Siglec-5), an inhibitory receptor on phagocytes.the polymorphism could influence the risk of prematurity among human fetuses of mothers colonized with GBS. This first functionally proven example of a paired receptor system in the Siglec family has multiple implications for regulation of host immunity.

Shipping Conditions:: Blue Ice