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RP00228

Recombinant Human RGMA Protein

Size

£133.00

SKU:
RP00228
Additional Names:
RGMA, RGM, repulsive guidance molecule A,RGM
Molecular Weight:
25-40, 60 kDa
Purity:
≥90%
Storage Conditions:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Immunogen:
Cys48-Gly422
Formulation:
Recombinant Human RGMA Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Cys48-Gly422) of human RGMA (Accession #NP_064596.2) fused with a 6xHis tag at the C-terminus.
Species:
Human
Sequence:
CKILKCNSEFWSATSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGPTSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDLPG
Uniprot:
Q96B86
Synonyms:
repulsive guidance molecule A;repulsive guidance molecule family member a;RGM;RGM domain family member A;RGM domain family, member A
Extra Details:
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.
Shipping Conditions:
Blue Ice