RP00215
Recombinant Human IGFBP-2 Protein
Size
£145.00
- SKU:
- RP00215
- Additional Names:
- IBP2, IGF-BP53,IGFBP2,IGF-BP53
- Molecular Weight:
- 37-39 kDa
- Purity:
- ≥95%
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Glu40-Gln328
- Formulation:
- Recombinant Human IGFBP-2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu40-Gln328) of human IGFBP-2 (Accession #NP_000588.2) fused with an initial Met at the N-terminus and a 6xHis tag at the C-terminus.
- Species:
- Human
- Sequence:
- EVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEKRRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFYNEQQEARGVHTQRMQ
- Uniprot:
- P18065
- Synonyms:
- IBP2;IGF-binding protein 2;IGF-BP53;insulin-like growth factor binding protein 2, 36kDa;insulin-like growth factor-binding protein 2
- Extra Details:
- IGFBP-2, also known as IGFBP2, is a insulin-like growth factor-binding protein (IGFBP). IGFBPs have a high affinity for IGFs. Some members of the IGFBP family have been consistently shown to inhibit IGF actions by preventing them from gaining access to the IGF receptors, while others potentiate IGF actions by facilitating the ligand-receptor interaction. IGFBP2 is overexpressed in many malignancies and is often correlated with an increasingly malignant status of the tumor, pointing to a potential involvement of IGFBP2 in tumorigenesis.
- Shipping Conditions:
- Blue Ice