Recombinant Human Serpin G1/Plasma protease C1 inhibitor Protein

Size

£127.00

SKU:: RP00197
Additional Names:: SERPING1, C1IN, C1INH, C1NH, HAE1, HAE2, serpin family G member 1,C1IN,C1INH,C1NH,HAE1,HAE2
Molecular Weight:: 90-100 kDa
Purity:: ≥95%
Storage Conditions:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Immunogen:: Met1-Ala500
Formulation:: Recombinant Human SerpinG1/C1 inhibitor/C1IN Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Ala500) of human SerpinG1/C1 inhibitor/C1IN (Accession #NP_000053.2) fused with a 6xHis tag at the C-terminus.
Species:: Human
Sequence:: MASRLTLLTLLLLLLAGDRASSNPNATSSSSQDPESLQDRGEGKVATTVISKMLFVEPILEVSSLPTTNSTTNSATKITANTTDEPTTQPTTEPTTQPTIQPTQPTTQLPTDSPTQPTTGSFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFVLWDQQHKFPVFMGRVYDPRA
Uniprot:: P05155
Synonyms:: C1 esterase inhibitor;C1-inhibiting factor;C1-inhibitor;C1IN;C1INH;C1NH;complement component 1 inhibitor;epididymis secretory sperm binding protein;HAE1;HAE2;plasma protease C1 inhibitor;serine/cysteine proteinase inhibitor clade G member 1;serpin G1;serpin peptidase inhibitor clade G member 1;serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Extra Details:: Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin).Serpin G1/C1 inhibitor is the physiological inhibitor of activated C1r and C1s and regulates activation of both the complement and contact systems. Deficiency of C1 inhibitor results in hereditary angioedema, which is characterized by recurrent episodes of localized angioedema of the skin, gastrointestinal mucosa or upper respiratory mucosa. C1 inhibitor may prove useful in a variety of other diseases including septic shock, reperfusion injury, hyperacute transplant rejection, traumatic and hemorrhagic shock, and the increased vascular permeability associated with thermal injury, interleukin-2 therapy and cardiopulmonary bypass.

Shipping Conditions:: Blue Ice