RP00194
Recombinant Human Serpin A3/Alpha-1-antichymotrypsin Protein
Size
£163.00
- SKU:
- RP00194
- Additional Names:
- AACT, ACT, GIG24, GIG25,SERPINA3,ACT,GIG24,GIG25
- Molecular Weight:
- 55-70 kDa
- Purity:
- ≥95%
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Asn26-Ala423
- Formulation:
- Recombinant Human Serpin A3/Alpha-1-antichymotrypsin Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Asn26-Ala423) of human Serpin A3/AACT (Accession #NP_001076.2) fused with a 6xHis tag at the C-terminus.
- Species:
- Human
- Sequence:
- NSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQA
- Uniprot:
- P01011
- Synonyms:
- AACT;ACT;alpha-1-antichymotrypsin;cell growth-inhibiting gene 24/25 protein;GIG24;GIG25;growth-inhibiting protein 24;growth-inhibiting protein 25;serine (or cysteine) proteinase inhibitor, clade A, member 3;serpin A3;serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
- Extra Details:
- SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors. It is synthesized primarily in the liver and secreted as one of the most abundant serpins in plasma. SerpinA3 deficiency has been associated with liver disease, and mutations of this gene have been observed in patients with Parkinson disease and chronic obstructive pulmonary disease. Serpin A3 is a major constituent of the plaques associated with Alzheimer's disease and an inhibitor of amyloid beta peptide degradation.
- Shipping Conditions:
- Blue Ice