Recombinant Human TNFRSF17/BCMA/CD269 Protein

Size

£181.00

SKU:: RP00155
Additional Names:: TNFRSF17,BCM,BCMA,CD269,TNFRSF13A
Molecular Weight:: 40-50 kDa
Purity:: ≥90%
Storage Conditions:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Immunogen:: Met1-Ala54
Formulation:: Recombinant Human TNFRSF17/BCMA/CD269 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Ala54) of human TNFRSF17/BCMA/CD269 (Accession #NP_001183.2) fused with an Fc, 6xHis tag at the C-terminus.
Species:: Human
Uniprot:: Q02223
Synonyms:: B cell maturation antigen;B-cell maturation factor;B-cell maturation protein;BCM;BCMA;CD269;TNFRSF13A;tumor necrosis factor receptor superfamily member 17
Extra Details:: Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.